St. Jude Medical, Cardiology Division, Inc., a subsidiary of Abbott Laboratories, is a company headquartered in St. Paul, MN, that develops and commercializes minimally invasive cardiovascular and neurovascular medical devices. The firm was founded by Paul R. Buckman. Lisa D. Earnhardt is currently the CEO of the company.

Avalon Medical AS, a subsidiary of Medu AS, is a Norwegian company located in Oslo. The firm distributes medical equipment. It was founded in 1997. Sturle Andre Ramvik Gr��nbeck is the current CEO, occupying that position since 2020. Avalon Medical AS was acquired by Medu AS on May 18, 2021.

Cardiovalve is a medical device company developing a transfemoral mitral valve replacement system. The flagship Cardiovalve system is the first one designed to replace the mitral valve using a transfemoral system. It is designed from the bottom up for transfemoral/transseptal delivery with femoral venous access. Cardivalve approach offers significant benefits, including a short profile for minimal protrusion to the left ventricle, minimizing interference in the cardiac blood flow and increased safety. It is currently evaluating the safety and performance of its system in clinical studies and it will seek EU and US approval.

Edwards Lifesciences Corp. engages in patient-focused medical innovations for heart disease and critical care monitoring. Its products are categorized into four main areas: Transcatheter Aortic Valve Replacement, Transcatheter Mitral and Tricuspid Therapies, Surgical Structural Heart, and Critical Care. It operates through the following geographical segments: United States, Europe, Japan, and Rest of World. The company was founded by Miles Lowell Edwards in 1958 and is headquartered in Irvine, CA.

Sino Medical Sciences Technology, Inc. engages in the research, development, production, and sale of interventional medical devices. It offers coronary stents and balloons, as well as neurovascular and structural heart disease products. The company was founded on September 21, 2007 and is headquartered in Tianjin, China.

KOKA Lifesciences Co., Ltd. is a company headquartered in Shanghai, China, that manufactures and sells medical devices. The firm was founded in 2018. Ming Ming Wu is currently the CEO of the company.

Evalve, Inc. engages in the design, development, manufacture, and marketing of devices that enable the repair of cardiac valves. It provides a non-surgical mitral valve repair system consisting of a steerable guide catheter, a clip delivery system, and an implant device that is used by interventional cardiologists to reduce mitral regurgitation. The company was incorporated in 1999 and is based in Menlo Park, California.

Cingular Biotech develops implantable and regenerative materials and devices. Cingular Biotech focuses on surgical valve replacement and repair with biomaterial technology, as well as transcatheter valves and other cardiovascular disease treatment fields.

Tendyne Holdings, Inc. is a clinical stage medical device company focused on the development of minimally invasive therapies for the treatment of mitral regurgitation. Mitral regurgitation is a condition that afflicts hundreds of thousands of individuals worldwide every year. Formed in 2010, their first product concept is a transcatheter mitral valve replacement prosthesis for the treatment of mitral regurgitation. The intent is for the valve to be deployed and secured with no disruption to the native mitral annulus while preserving the sub-valvular apparatus. Placement of the valve is intended to be completed transapically in a simple procedure where the implanting physician is able to re-position, remove, and re-deploy their valve throughout the procedure.

Gross & Co. provided legal services. The company was headquartered in Suffolk, the United Kingdom.

Fasotec develops and markets internet software and services. It designs, develops, and markets CAD/CAM/CAE software. The company is also engaged in prototyping, mold design, and development of production technology. Fasotec was founded in 1983 and is based in Chiba-shi, Japan.

Venus MedTech (HangZhou) Inc. is located in Hangzhou National High-tech Industrial Development Zone (Binjiang), with its products positioned in the development and industrialization of international advanced interventional artificial cardiac valve system, filling up the blank in China. Interventional artificial aortic valve products researched and developed by the company takes the lead in finishing clinical tests in China. In reference to the development and promotion conditions of coronary stents at home and abroad, interventional artificial cardiac valve, as a revolutionary treatment means, has been increasingly recognized by experts, and will take on an explosible increase of clinical needs in the foreseeable next few years.

MicroPort CRM SRL engages in the production and distribution of medical devices. It specializes in the development of medical technologies for the treatment of cardiovascular diseases. The company is headquartered in Saluggia, Italy.

Jenscare Scientific Co., Ltd. is a holding company, which engages in the development and sale of transcatheter aortic valve systems. Its products include transcatheter prosthetic three tricuspid valve system and transcatheter aortic valve system. The company was founded on November 8, 2011 and is headquartered in Ningbo, China.

Sino Xinchang Medical Technology Co., Ltd., established on 2020-10-09, Business scope includes licensed projects:Import and export;Technology Import and Export;Import and export agency;Class III medical device business;Production of Class II Medical Devices;Production of Class III Medical Devices(Items subject to approval by law,Business activities can only be carried out after approval by relevant departments,Specific business projects are subject to approval results) General project:Technical Services,technology development,technical consulting,Technology Exchange,technology transfer,Technology Promotion;Sales of Class II Medical Devices(Except for projects subject to approval by law,Carry out business activities independently in accordance with the law with a business license)

Cephea Valve Technologies, Inc. provides catheter delivered mitral valve regurgitation products/heart valves for the treatment of coronary artery disease in patients. It offers catheter based therapies, such as balloons and stents for aortic valves replacements. The company was incorporated in 2011 and is based in San Jose, California.

Boston Scientific Scimed, Inc. develops, manufactures, and markets medical devices used principally to treat cardiovascular disease.

Corcym Srl is a company headquartered in Milan, Italy, that designs and manufactures surgical medical devices. Christian Paolo Mazzi is currently the CEO of the firm.\nThe company says this about itself: CORCYM is a global, independent, medical device company entirely focused on state-of-the-art surgical solutions to fight structural heart disease. CORCYM has a presence in more than 100 countries with approximately 850 employees and ensures strong continuous support to patients, healthcare professionals and healthcare systems worldwide.