Smith & Nephew PLC designs, manufactures and markets orthopedic devices, sports medicine and ENT technologies, and wound-care solutions. Slightly more than 40% of the U.K.-based firm's revenue comes from orthopedic products, and another 30% is a sports medicine and ENT. The remaining 27% of revenue is from the advanced wound therapy segment. Roughly half of Smith & Nephew's total revenue comes from the United States, just over 30% is from other developed markets, and emerging markets account for the remainder.

Eli Lilly engages in the discovery, development, manufacture, and sale of products in the pharmaceutical products business segment. The company manufactures and distributes products through owned or leased facilities in the United States, Puerto Rico, and 25 other countries. Its products are sold in approximately 135 countries. It also conducts research to find products to treat diseases in animals and to increase the efficiency of animal food production.

Radius is a leading company in the discovery and development of a new generation of drug therapies for osteoporosis and women's health. The company's first drug in clinical trials is designed to build new bone in patients with osteoporosis, with the goal of reducing the risk of future fractures and improving the quality of life. Their long-term focus is on additional areas in women's health that include symptoms of menopause, reproductive disorders, and frailty associated with aging. Radius's scientific leadership includes some of the world's leading researchers in the fields of bone metabolism, endocrinology, and medicinal chemistry, and the company has a broad foundation in nuclear hormone receptors.

Synthesis BV engages in the design and production of synthetic water level regulation products. It offers penstocks, pipeline valves, accessories, channel slide gates, fish migration, float units, overflow pits, pivoted weirs, pipes, dirt grates, butterfly valve, and check valves. The company is headquartered in Emmeloord, the Netherlands.

Synthes USA LP used to manufacture medical devices. The company was founded by Hansjörg Wyss in 1974 and is headquartered in West Chester, PA.

DePuy Synthes Products, Inc. develops and markets medical products. It offers distal volar Radius, which is designed to treat distal radius fractures, dorsal endoplate, an invasive dorsal nail plate that provides fixed angle support and intramedullary locked fixation with a duplicate and reproducible surgical procedure, spatial subchondral support plate, which is used to treat proximal humeral fractures and Small Bone Fixation System, a percutaneous locked intramedullary nail system for metacarpals and the phalanges. The company was founded on June 22, 2004 and is headquartered in Wilmington, DE.

Conventus Orthopaedics provides a range of orthopedic and sports medicine services. The physicians specialize in orthopedic surgery, reconstructive surgery, spine surgery, joint replacement, sports medicine, physical therapy, and operative care of fractures, arthritis, strains, sprains, and sports-related injuries. Conventus was formed by a team of medical professionals with the sole purpose of creating less invasive ways to treat challenging periarticular fractures. By leveraging advanced nitinol technology, the Conventus team has developed a platform technology that provides robust fixation and creates reliable repairs. The company was incorporated in 2009 and is based in Maple Grove, Minnesota.

Orthogrid Systems Holdings LLC provides health care services. The company was founded in 2015 and is headquartered in Salt Lake City, UT.

Kindeva Drug Delivery LP engages in the pharmaceutical contract development and manufacturing. It is also involved in the formulation, product development, scale up manufacturing, and commercial manufacturing. The company was founded by William Riker in 1846 and is headquartered in St. Paul, MN.

Kyphon produces medical devices to treat and restore spinal anatomy using minimally invasive technology. It is engaged in developing surgical systems, apparatus and methods for mixing materials, instruments and methods for forming a cavity, and other products related to its industry. Kyphon operates as a subsidiary of Medtronic, Inc.It is based in Switzerland.

Part of Zimmer Biomet Holdings, Inc., Biomet CV is a Dutch company. The firm manufactures medical instrument and aids.

Orthofix SRL manufactures and markets medical devices. The company was founded byGiovanni de Bastiani in 1980 and is headquartered in Bussolengo, Italy.

Merck & Co., Inc. is a health care company, which engages in the provision of health solutions through its prescription medicines, vaccines, biologic therapies, animal health, and consumer care products. It operates through the following segments: Pharmaceutical, Animal Health, and Other. The Pharmaceutical segment includes human health pharmaceutical and vaccine products. The Animal Health segment discovers, develops, manufactures, and markets animal health products, such as pharmaceutical and vaccine products, for the prevention, treatment and control of disease in livestock, and companion animal species. The Other segment consists of sales for the non-reportable segments of healthcare services. The company was founded in 1891 and is headquartered in Kenilworth, NJ.

Shanghai Laiying Medical Technology Co., Ltd., established on 2018-08-29, The scope of business includes engaging in medical technology,artificial intelligence robotics,data technology,Material Technology,Computer and software and hardware technology,network technology,IoT technology,Technical services in the field of electronic technology,technology development,technical consulting,technology transfer(Do not engage in medical activities),Big data service,computer system integration,Leasing of Class I Medical Devices(Not to engage in financial leasing),product design,Electronic Component,Mechanical equipment and accessories,Electromechanical equipment and accessories,metallic material,digital product,electronic product,communication equipment,Sales of Class I Medical Devices. [Items subject to approval by law,Business activities can only be carried out after approval by relevant departments]

Biomet Manufacturing LLC manufactures and markets surgical and non-surgical products. The firm operates in one reportable business segment musculoskeletal products, which includes the design, manufacture and marketing of products in five product categories large joint reconstructive, sports, extremities, trauma spine and bone Healing, and dental products. The company is headquartered in Warsaw, IN.

OsteoMed Corp. manufactures medical devices and surgical implants for oral maxillofacial, neuro & orthopedic surgery. Its products include craniomaxillofacial, distraction osteogensis, small bone orthopedic, neurosurgical, ostebiologics, surgical power, and osteomatch. The company is headquartered in Dallas, TX.

Hand Innovations LLC manufactured medical and surgical products used for fracture fixations. Its products include distal volar radius, dorsal nail plate, small bone fixation system, and proximal humerus. The company was founded by Jorge L. Orbay in 2001 and was headquartered in Miami, FL.