Macroglobulinemia is the presence of increased levels of macroglobulins in the circulating blood. It is a plasma cell dyscrasia, resembling leukemia, with cells of lymphocytic, plasmacytic, or intermediate morphology, which secrete a monoclonal immunoglobulin M component. There is diffuse infiltration by the malignant cells of the bone marrow and also, in many cases, of the spleen, liver, or lymph nodes. The circulating macroglobulin can produce symptoms of hyperviscosity syndrome: weakness, fatigue, bleeding disorders, and visual disturbances. Peak incidence of macroglobulinemia is in the sixth and seventh decades of life. (Dorland, 28th ed)
Board of Trustees of The University of Arkansas
Part of University of Arkansas System, Board of Trustees of The University of Arkansas is a company headquartered in Fayetteville, AR, that owns and operates radio stations.
Bristol-Myers Squibb Company, through its subsidiaries, engages in the discovery, development, licensing, manufacturing, marketing, distribution, and sale of pharmaceuticals and nutritional products.
The company operates in two segments, Pharmaceuticals, and Nutritionals. The Nutritionals segment is operated through the company's subsidiary Mead Johnson Nutrition Company (Mead Johnson). The Pharmaceuticals segment is made up of the global pharmaceutical and international consumer medicines business.
Medicine
Oncology drugs
Clinical trial
Immunotherapy
Cardiovascular agent
Monoclonal antibody
Cancer immunotherapy
Bevacizumab
Biopharmaceutical
Insulin aspart
Drug discovery
Antiviral drug
Anticoagulant
Cardiology
Heparin
Drug development
Genomics
Cephalosporin
Stroke
ZymoGenetics, Inc.
http://www.zymogenetics.com
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ZymoGenetics is focused on the discovery, development, and early manufacture of therapeutic proteins. ZymoGenetics is a fully-integrated research and development organization with a broad range of skills and technologies, including scientific computing, molecular and cellular biology, protein chemistry, antibody generation and engineering, clinical development and operations, regulatory affairs, quality, drug formulation, process development and protein manufacturing.
Medicine
Pharmacy and Therapeutics
Protein chemistry
Therapeutic protein
Bevacizumab
Regulatory affairs
Process development
Antibody
Thalidomide
Lenalidomide
Pembrolizumab
Blinatumomab
Drug
Cancer immunotherapy
Immunotherapy
Monoclonal antibody
Oncology drugs
Clinical trial
Ligation clip
Wound healing
Glenmark Pharmaceuticals SA
http://www.glenmarkpharma.com
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Glenmark Pharmaceuticals SA, part of Glenmark Pharmaceuticals Ltd., is a Swiss company located in Neuch��tel. The firm develops and Manufactures pharmaceuticals.
Janssen Pharmaceutica NV
http://www.janssen.com/belgium
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Janssen Pharmaceutica is a pharmaceutical company headquartered in Beerse, Belgium and owned by Johnson & Johnson. It was founded in 1953 by Paul Janssen. In 1961, Janssen Pharmaceutica was purchased by New Jersey-based American corporation Johnson & Johnson, and became part of Johnson & Johnson Pharmaceutical Research and Development (J&J PRD), now renamed to Janssen Research and Development (JRD), which conducts research and development activities related to a wide range of human medical disorders, including mental illness, neurological disorders, anaesthesia and analgesia, gastrointestinal disorders, fungal infection, HIV/AIDS, allergies and cancer. Janssen and Ortho-McNeil Pharmaceutical have been placed in the Ortho-McNeil-Janssen group within Johnson & Johnson Company.
Product design
Neuroscience
Pharmacy and Therapeutics
Neurological disorder
Mental illness
Therapeutic Area
Medicine
Biomedicine
Biotechnology
Deck
Antifungal drug
Contract research organization
Companion diagnostic
Exosome
Infection drug
Clinical research
Immunotherapy
Biophysics
Antifungal
Shanghai Kanda Biotechnology Co., Ltd.
Shanghai Kangdai Biomedical Technology Co., Ltd., established on 2009-04-17, Business scope includes research and development of biomedicine,Biotechnology Services,Engaged in the import and export business of goods.
[Items subject to approval by law,Business activities can only be carried out after approval by relevant departments]
Pharmacyclics LLC
http://www.pharmacyclics.com
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Pharmacyclics Inc. is a clinical-stage biopharmaceutical company focused on discovering and developing innovative small-molecule drugs for the treatment of cancer and immune mediated diseases.
Medicine
Drug
Oncology drugs
Biopharmaceutical
Cancer
Bruton's tyrosine kinase
Biotechnology
Biomedicine
Kinase
Oncogene
Enzyme
Immunotherapy
Monoclonal antibody
Clinical trial
Breakthrough therapy
Chronic lymphocytic leukemia
ATP-binding cassette transporter
Leukemia
DNA damage
SBI Biotech Co., Ltd.
http://www.sbibiotech.jp
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SBI Biotech mainly focuses on dendritic cell platform-based innovative drug development.
As an R&D-type bio-venture company, we do not have abundant human resource like in the case of general pharmaceutical companies and we mainly focus on our activity in the early stages of drug development. Particularly, our biggest hurdle is the clinical studies / clincal trials which we need huge budgets to support our clinical trials on human to test drug safety and efficacy.
We have been trying to utilize our human and financial resources efficiently by early licensing of our pipelines in the preclinical stage, instead of performing the clinical trials by our own. For the early stage licensing, we have tried to provide excellent products by the world-leading research team with the expertise in dendritic cell manipulation. We have successfully proven the feasibility of the business model since we succeeded in licensing of our early stage dendritic cells targeting antibody, anti-ILT7 antibody to MedImmune. We will continue our efforts in early licensing activity by our highly competitive research team.
Dendritic cell
Clinical trial
Drug development
Tocilizumab
Rituximab
Antibody
Toll-like receptor
Chemokine receptor
Anakinra
Leflunomide
Colony-stimulating factor
Abatacept
Tofacitinib
Interleukin
Methotrexate
Sulfasalazine
Corticosteroid
Drug
Anthrogenesis Corp.
http://anthrogenesis.com
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Anthrogenesis, based in Cedar Knolls, New Jersey, is a biotherapeutics company that has developed proprietary methods for collecting, processing and storing stem cells and other valuable biomaterials derived from human placental tissue. Anthrogenesis is focused on developing and delivering therapies using stem cells sourced from human placental tissue to treat cancers and immunological, metabolic and inflammatory diseases. Anthrogenesis has demonstrated that the human placenta is an abundant source of biotherapies, including early stage stem cells and other biomaterials for organ and tissue repair. Anthrogenesis also operates Lifebank, a state-licensed blood bank that banks stem cell transplant units derived from placental tissue and in some cases, blood from the umbilical cord that is collected immediately after birth.
Stem cell
Pharmacy and Therapeutics
Placenta
Umbilical cord
Proprietary Method
Regenerative medicine
Cancer
Biotechnology
Millennium Pharmaceuticals, Inc.
http://www.takedaoncology.com
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In 2008, Takeda Pharmaceutical Company Limited acquired Millennium Pharmaceuticals and the resulting company became exclusively focused on oncology. In 2014, Takeda Oncology was created to become the global headquarters for Takeda’s oncology specialty business unit, in Cambridge, Massachusetts, on the former Millennium Pharmaceuticals site. At Takeda Oncology they endeavor to deliver novel medicines to patients with cancer worldwide through our commitment to science, breakthrough innovation and passion for improving the lives of patients.
This singular focus drives our aspirations to discover, develop and deliver breakthrough oncology therapies. By concentrating the power of leading scientific minds and the vast resources of a global pharmaceutical company, they are finding innovative ways to improve the treatment of cancer.
They've built a portfolio of paradigm-changing therapies and a leading oncology pipeline. Though They've made great strides in our fight against cancer, they are determined to do more — to work harder and to reach higher. They continue to seek our aspirations with the same passion, agility and entrepreneurial spirit that has sustained our patient-centric culture and has made us the leaders in oncology that they are today.
Good health and a happy life is something all people rightly aspire to. They believe everyone on the planet deserves access to quality health care.
Finding affordable solutions to today's health care challenges demands cutting-edge science, highly talented and motivated people and above all the ability to innovate. Innovation and continuous improvement are the heartbeat of their company.
Their mission is to make health care more affordable, increasing access to important medicines through the provision of high quality small molecule generics, and new biological and new chemical entities.
Medicine
Antibody-drug conjugate
Clinical trial
Synthon
Oncology drugs
New chemical entity
Heartbeat
Small molecule
Monoclonal antibody
Biosimilar
Breast cancer
Pharmaceutical manufacturing
Zaleplon
Eszopiclone
Trastuzumab
Zolpidem
Ipatasertib
Biomedicine
Antihistamine
Shanghai Celgen Bio-pharmaceutical Co., Ltd.
http://www.celgenpharm.com
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Shanghai Celgen Biopharma Co., Ltd. (上海赛金) is mainly engaged in the research and development, production, and sales of biological medicinal products of recombinant proteins and monoclonal antibodies used in the field of immune disease and cancer.
As a biopharmaceutical enterprise engaged professionally in researching and developing, producing, and selling biopharmaceutical products, Celgen Biopharma has already built up a professional platform for the phages antibody screening library, a CHO cell clone development platform recognized by FDA/EMEA, and a world-class platform to culture CHO cells without serum or antibiotics, an advanced purification platform, a complete analysis platform, a technology development platform of ""quality stems from design"", a vitro drug active research platform, and a vivo activity evaluation technology platform.
Medicine
Monoclonal antibody
Phage antibody
Cell Clone
Antibiotics
Antibody
Cell
Drug
Triphase Research & Development I Corp
Suzhou Yuntai Biomedical Technology Co., Ltd.
Suzhou Yuntai Biomedical Technology Co., Ltd., established on 2013-01-06, Business scope includes biotechnology products,Research and development of in vitro diagnostic reagents and related equipment,technology transfer,Technical Services;biotechnology product(non-medical,non edible),Sales of laboratory equipment and consumables.Production,Sales:Class I medical device,Class II medical device,Class III medical devices.(Items subject to approval by law,Business activities can only be carried out after approval by relevant departments)
Alaunos Therapeutics, Inc.
ZIOPHARM Oncology is an American biopharmaceutical company headquartered in Boston, Massachusetts, that develops novel therapeutics for the treatment of cancer. ZIOPHARM has three oncology therapeutics in clinical development: IL-12 DNA, indibulin and darinaparsin. In 2011, ZIOPHARM established a partnership with Intrexon Corporation to develop and commercialize DNA therapeutics based on Intrexon's synthetic biology technology platform. The exclusive channel partnership between Intrexon and ZIOPHARM has been established specifically for the field of human oncologic therapeutics. Under the partnership, ZIOPHARM will be responsible for conducting preclinical and clinical development of candidates, as well as for other aspects of manufacturing and the commercialization of the candidates.
Oncology
Medicine
Pharmacy and Therapeutics
DNA
Cell therapy
Genomics
Synthetic biology
Oncology drugs
Biopharmaceutical
Cancer therapy
Biotechnology
Gene delivery
Immunotherapy
Cancer immunotherapy
Monoclonal antibody
Viral vector
Bevacizumab
CRISPR
Plasmid
Transfection
Olon is one of the largest European developers and manufacturers, supplying APIs for the pharmaceutical industry worldwide both, for Generic as well as for contract manufacturing.
OLON owns 5 manufacturing sites in northern Italy (Rodano, Settimo Torinese, Garbagnate Milanese, Mulazzano and Dorno) with more than 800 employees while INFA Group, with more than 400 employees, has 2 manufacturing sites in Italy, Labochim and Sifavitor, and 1 in Spain, Derivados Químicos.
Pharmaceutical manufacturing
Biology
Medicine
Good manufacturing practice
Active ingredient
Contract research organization
Dosage form
Tretinoin
Monoclonal antibody
Travatan Z
Generic drug
Liposome
Bioavailability
Antibody-drug conjugate
Biomedical engineering
Cell therapy
Coating
Oncology drugs
Biopharmaceutical
Manufactures pharmaceuticals and diagnostic substances
Medicine
Botanical drug
Herb
Knopp Biosciences is a drug discovery and development company that focuses on delivering breakthrough treatments in neurological disorders through innovation, experience, and partnership. The company targets diseases imposing high costs on the healthcare system, with patient populations clearly identifiable using validated biomarkers or genetic testing. The company's goal is to accelerate and advance treatment, change the course of diseases, and improve the lives of the patients and their families.
Knopp Biosciences was founded in 2004 and is headquartered in Pittsburgh, Pennsylvania.
Clinical trial
Drug discovery
Neurological disorder
Medicine
Biomedicine
Biotechnology
Genetic testing
Neuroscience
Biophysics
Dementia
Pharmaceutics
Aptamer
Drug design
Cancer research
Toxicology
Clinical research
Immunotherapy
Drug development
Acerta Pharma BV
http://www.acerta-pharma.com
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Acerta Pharma BV develops drugs for oncology and autoimmune diseases. It operates as a biotech company that combines technology platforms in drug discovery and development such as the covalent technology platform and the multiparametric phosphoflow cytometry platform. The company was founded by Allard Kaptein in 2012 and is headquartered in Oss, Netherlands.
Medicine
Pharmacy and Therapeutics
Autoimmune disease
Drug discovery
Oncology drugs
Oncology
Cytometry
Immunotherapy
Monoclonal antibody
Bruton's tyrosine kinase
Biotechnology
Kinase
Drug
Biomedicine
Enzyme
Cancer immunotherapy
Cell therapy
Bionics
Biopharmaceutical
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