Action Pharma A/S is an R&D-focused biotech company located in the Nordic Medicon Valley area in Copenhagen, Denmark. Action Pharma was founded in 2000 and has a pipeline of 4 drug candidates in different stages of development, plus additional compounds in discovery and early preclinical development.\nAction Pharma pursues the discovery and development of new drugs and treatment concepts to treat cardiovascular diseases, inflammatory diseases and metabolic diseases, such as type-II diabetes and obesity. Its drug candidates are modified endogenous peptides with improved efficacy and small chemical entities targeted the melanocortin receptors.\nIn disease models, its drug candidates have shown strong effects in treating and preventing inflammation and organ damage in conditions such as post-surgical organ dysfunction and acute myocardial infarction. A major focus for Action Pharma is treatment candidates for type-II diabetes, obesity and metabolic syndrome. Moreover, several drug candidates have shown effects in treating inflammatory diseases, such as rheumatoid arthritis, inflammatory bowel disease, multiple sclerosis and dermatitis.

Beth Israel Deaconess Medical Center (BIDMC) in Boston, Massachusetts is a teaching hospital of Harvard Medical School. It was formed out of the 1996 merger of Beth Israel Hospital (founded in 1916) and New England Deaconess Hospital (founded in 1896). Among independent teaching hospitals, Beth Israel Deaconess Medical Center consistently ranks in the top three recipients of biomedical research funding from the National Institutes of Health. Research funding totals nearly $200 million annually. BIDMC researchers run more than 850 active sponsored projects and 200 clinical trials. The Harvard-Thorndike General Clinical Research Center, the oldest clinical research laboratory in the United States, has been located on this site since 1973.

Longeveron is a life-sciences company that develops biological solutions for aging and aging-associated diseases. This is through the testing of allogeneic human Mesenchymal Stem Cells (MSCs) that are derived from the bone marrow of young, healthy donors. The Longeveron-grown Mesenchymal Stem Cell (LMSCs) product is manufactured in Longeveron’s cell processing facility located in Miami, Florida.

Roche Diagnostics GmbH, part of Roche Holding AG, is a company headquartered in Mannheim, Germany, involved in laboratory analytical instruments. Andreas Schmitz and Claus Haberda are the current co-CEOs of the firm. On January 01, 1999 Roche Holding AG acquired Roche Diagnostics GmbH.

Academisch Ziekenhuis Maastricht operates as medical research centre. The company is headquartered in Maastricht, the Netherlands.

Solvay SA engages in the manufacture and distribution of chemical and plastic products. It operates through the following segments: Advanced Formulations, Advanced Materials, Performance Chemicals and Corporate and Business Services. The Advanced Formulations segment offers specialty formulations that impact surface chemistry and alter liquid behavior. The Advanced Materials segment materials for multiple applications primarily in the automotive, aerospace, electronics and health markets. The Performance Chemicals segment operates in mature and resilient markets and has positions in chemical intermediates. The Corporate and Business Services segment includes corporate and other business services, such as the research & innovation center. The company was founded by Ernest Solvay in 1863 and is headquartered in Brussels, Belgium.

BG Medicine, Inc. is a life sciences company. It engages in developing and delivering innovative solutions for healthcare providers that provide insight and transform the clinical care of heart failure and related disorders. The firm distributes products such as BGM Galectin-3 to clinical laboratories, hospitals, and healthcare providers. The company was founded in February 2000 by Jan van der Greef and is headquartered in Foxboro, MA.

Dornier MedTech Systems GmbH is a private company headquartered in Wessling, Germany, with a presence in Japan and Germany, that wholesales medical and orthopaedic articles. The firm was founded by Claude Dornier. Goh Siew Hoon and Boon Thong Abel Ang are the current co-CEOs of the company.

Advanced Cardiovascular Systems, Inc. develops and manufactures cardiovascular medical products. It operates as a subsidiary of Abbott Laboratories. Its medical devices help patients with heart diseases in returning to active and productive lives and physicians for improving patient management and clinical outcomes. Advanced Cardiovascular Systems, Inc. is based in Santa Clara, California. it is currently known as Abbott Cardiovascular Systems.

Founded in San Diego, Calif., in 2013, CardioCell LLC is a global biotechnology company that explores therapeutic applications of unique patented ischemia-tolerant mesenchymal stem cells (itMSCs) manufactured under cGMP conditions. CardioCell has an exclusive worldwide license from its parent company, Stemedica, for exploration of therapeutic indications in the cardiovascular field, which includes such indications as acute myocardial Infarction (AMI), chronic heart failure (CHF) and peripheral artery disease (PAD).

Firalis is a biotechnology company, creating novel values via biomarker discovery, development and regulatory qualification that ultimately lead to biomarker-based diagnostics. With a comprehensive expertise in the field, Firalis develops biomarkers and biomarker-based diagnostic kits to improve disease outcomes and patient comfort, increase therapeutic decisions and finally to reduce healthcare costs remarkably, being the principle goals of biomarker services offered by Firalis. The activities of Firalis mainly, but not exclusively, involve biomarkers that are related to inflammatory disorders including common diseases such as atherosclerosis, rheumatoid arthritis or rare/orphan diseases such as systemic or autoimmune vasculitis. A major part of their activities cover drug-induced organ injuries in particular kidney, liver and vasculature, as major drug targets. Firalis owes its leading position to a unique network of clinical centers of excellence that it established to conduct studies of biomarker qualification in clinics. At Firalis, they exclusively invest on projects with highest potential of success for biomarker-based diagnostics that will allow us to launch its first high-value diagnostic kits within short terms. The company is located in Huningue, a vibrant Alsatian town in the heart of BioValley at the triple border of France, Germany and Switzerland, next to Basel, the pharmaceutical capital of Europe.

Roche Diagnostics Corp. develops and manufactures diagnostic products. It offers anticoagulation management, blood gas and electrolytes, cholesterol and urinalysis products. The firm provides a broad portfolio of tools that help healthcare providers in the prevention, diagnosis and management of diseases like HPV, HIV, heart failure and diabetes, as well as other medical conditions, such as fertility and blood coagulation. Its products and services uses by researchers, physicians, patients, hospitals and laboratories worldwide. The company was founded in 1964 by Willard Eason and is headquartered in Indianapolis, IN.

Luxembourg Institute of Health is a private company headquartered in Strassen, Luxembourg. The firm operates as a public biomedical research organization. Ulf Nehrbass is currently the CEO of the company.

Edwards Lifesciences Corp. engages in patient-focused medical innovations for heart disease and critical care monitoring. Its products are categorized into four main areas: Transcatheter Aortic Valve Replacement, Transcatheter Mitral and Tricuspid Therapies, Surgical Structural Heart, and Critical Care. It operates through the following geographical segments: United States, Europe, Japan, and Rest of World. The company was founded by Miles Lowell Edwards in 1958 and is headquartered in Irvine, CA.

Heart Metabolics Ltd. operates as a biopharmaceutical company that engages in developing new treatments for orphan disease including cardio-metabolic diseases. The firm provides drugs to treat heart failure for hypertrophic cardiomyopathy patients. The company was founded by Michael Paul Frenneaux and Houshman Ashrafian in 2004 and is headquartered in Dublin, Ireland.

Pfizer Inc. (NYSE: PFE, /ˈfaɪzər/) is an American multinational pharmaceutical corporation headquartered in New York City was founded in 1849, based in New York City and was listed on New York Stock Exchange. It is one of the world's largest pharmaceutical companies. It is listed on the New York Stock Exchange, and its shares have been a component of the Dow Jones Industrial Average since 2004. Pfizer ranked No. 57 on the 2018 Fortune 500 list of the largest United States corporations by total revenue.

The University of California is the nation's best public university system, delivering top-notch research and innovation to California (and the world).

F. Hoffmann-La Roche Ltd. manufactures pharmaceutical products. It offers pharmaceutical drugs, pharmaceutical instruments, and diagnostics solutions. The company was founded by Fritz Hoffmann-La Roche on October 1, 1896 and is headquartered in Basel, Switzerland.