AstraZeneca has always believed in science, inspires infinite possibilities, and puts science at the top of all work. AstraZeneca's strategically important core treatment areas, and are committed to exploring pathogenic mechanisms, treatment methods, and innovative drugs, so that science can change people's lives and bring it to the medical industry Significant changes.

Boston Scientific Neuromodulation Corp. offers implantable pain management devices for neuromodulation. The company is headquartered in Marlborough, MA.

Camurus AB operates as a research based pharmaceutical company. The firm engages in the research, development and commercialization of specialty medicines. It provides its products for the treatment of severe and chronic conditions, which includes opioid dependence, pain, cancer and endocrine disorders. The company was founded by Kare Larsson in 1991 and is headquartered in Lund, Sweden.

Avent, Inc., a subsidiary of Avanos Medical, Inc., is an American company that develops and manufactures pharmaceuticals.

Grünenthal GmbH engages in the research and development of pharmaceutical products. It specializes in pain, gout, and inflammation. The company was founded by Hermann Wirtz in 1946 and is headquartered in Aachen, Germany.

ZYUS is a biopharmaceutical company that offers patients cannabinoids and other phytotherapeutic medical solutions. The company elevates cannabinoids as a medical solution to alleviate suffering in patients who are experiencing discomfort due to chronic disease, treatment side effects, or conditions related to aging. It aims is to shift the paradigm from the treatment of physical disease to caring for overall well-being, by accelerating the adoption of phytotherapeutics. The company uses science as a driver to establish phytotherapeutics as a standard of care for treating disease and managing the experience of it. The company was founded in 2018 and is headquartered in Saskatoon, Saskatchewan.

Royce Medical Co. designs, manufactures and markets orthopedic products. It holds patented technology solutions in orthopedics, fracture management and wound care products. The company's products treat sprains, strains, fractures and post-operative care. It also manufactures short leg walkers, wrist splints, thumb spikes and other orthopedic braces and supports. Royce Medical was founded in 1968 and is headquartered in Camarillo, CA.

I-Flow Corp. designs, develops and manufactures ambulatory drug delivery systems. Its products include portable infusion pumps, catheters and pain kits. The company was founded in 1985 and is headquartered in Lake Forest, CA.

Pacira Cryotech, Inc. develops novel technologies for treatment of peripheral nerves. Its iovera treatment harnesses the power of cold with the Focused Cold Therapy delivery system and delivers immediate results for both therapeutic and aesthetic applications. The firm’s iovera treatment does not use toxins, chemicals, or pharmaceuticals to achieve results and leaves nothing behind in the body. The company was founded by Lisa Elkins in 2005 and is headquartered in Fremont, CA.

ALZA Corp. is a pharmaceutical and medical systems company that develops, manufactures, and markets therapeutic systems. It provides oral, transdermal, implantable, and liposomal technologies. It is also focused on drug delivery systems with over 20 prescription pharmaceutical products. With over 10,000 employees, ALZA Corp. is a subsidiary of Johnson & Johnson. It was established in 1968 by Dr Alejandro Zaffaroni. It is based inVacaville, California.

Relevare Aust Pty Ltd. develops innovative methods to treat diseases. The company was founded on August 9, 2004 and is headquartered in Abbotsford, Australia.

DURECT is a specialty pharmaceutical company developing innovative drugs for pain and chronic diseases, with late-stage development programs including REMOXY®, POSIDUR™, ELADUR®, and TRANSDUR®-Sufentanil. DURECT’s proprietary oral, transdermal and injectable depot delivery technologies enable new indications and superior clinical/commercial attributes such as abuse deterrence, improved convenience, compliance, efficacy and safety for small molecule and biologic drugs

Acadia Pharmaceuticals Inc. is a biopharmaceutical company focused on the development and commercialization of small molecule drugs for the treatment of central nervous system disorders. The Company maintains two wholly owned subsidiaries: Acadia Pharmaceuticals AB based in Malmo, Sweden and Acadia Pharmaceuticals A/S based in Denmark. The Company is developing a portfolio consisting of four product candidates, including the compound, pimavanserin, which it is developing for three separate neurological and psychiatric indications in collaboration with Biovail Laboratories International SRL (Biovail), a subsidiary of Biovail Corp. The indications are Parkinson's disease psychosis, which is in Phase III development, adjunctive therapy in schizophrenia, and Alzheimer's disease psychosis, for which it is initiating a Phase II feasibility study.

Klaria Pharma Holding AB engages in the development and commercialization of pharmaceutical products for migraine and cancer-related pain. Its operation is based on a patented drug delivery platform in the form of an alginate-based polymer film. The firm's project portfolio currently includes various pain states, opioid overdoses, cannabinoids, and allergic shock. The company was founded by Scott Boyer in 2015 and is headquartered in Uppsala, Sweden.

Spinal Modulation, Inc. provides medical devices research and development services. The company is based in Menlo Park, California. According to the 2002 Health Assessment on the Prevalence of Chronic Pain, severe chronic pain, as defined by the International Association for the Study of Pain, is prevalent in 10 to 13% of the adult population. Limited treatment options exist for these patients and the burden to the healthcare system is unsustainable. The Spinal Modulation AxiumTM Neurostimulator System is a next-generation intraspinal neuromodulation therapy that stimulates the dorsal root ganglion (DRG) to provide a new pain management option. It has shown promising results in managing chronic intractable leg pain, as well as difficult-to-target anatomies such as the back and foot. By stimulating the DRG, therapy can be adjusted to cover either broad or specific areas of pain throughout the torso and legs, while limiting uncomfortable postural effects typically experienced with other spinal cord stimulators.

Compex Technologies, Inc. designed and manufactured equipment for pain management, muscle rehabilitation and athletic training for consumer, sports training, clinical, sports medicine and home health uses. The company was founded in 1972 and was headquartered in New Brighton, MN.

Compex Medical SA, a subsidiary of Enovis Corp., is a company headquartered in Switzerland specializing in orthopedic, prosthetic, and surgical appliances and supplies.

Competitive Technologies, Inc. provides distribution, patent and technology transfer, sales and licensing services focusing on the needs of its customers. The Company develops relationships with universities, companies, inventors and patent or intellectual property holders to obtain the rights or a license to their intellectual property (technologies), or to their product. It also develops relationships with those who have a need or use for technologies or products. Its life science portfolio includes pharmaceuticals, biotechnologies, and medical devices. The Company earns revenue in two ways: retained royalties from licensing its clients and the Company’s own technologies to its customer licensees, and sales of finished products. Its services are beneficial to the inventor, manufacturer and distributor of the product. It earns revenue on a per-unit basis through product distribution agreements. The Company shares the revenue with the product inventor, and/or manufacturer.