ProtEmbo is designed to be a simple and reliable solution for one of the most feared complications during TAVR. The advent of transcatheter treatments for valvular heart disease has been a major revolution in the care of patients with disabilities or intercurrent illnesses that precluded undergoing stressful open cardiac surgical procedures. Nonetheless, in spite of ongoing improvements in TAVR procedures and outcomes, the occurrence of cerebrovascular events represents a significant morbidity of TAVR. Protembis was founded based on the vision to reduce the risk of cerebrovascular events, thereby improving outcomes and making TAVR even safer – especially in light of TAVR shifting to younger and lower-risk patients. The ProtEmbo System is an adjunctive device used during TAVR and removed following completion of valve implantation. The ProtEmbo is an intra-aortic filter device that is designed to deflect embolic material arising during TAVR away from the cerebral circulation.

JOTEC develops, produces, and markets medical devices for aortic and peripheral vascular disease. JOTEC’s product portfolio encompasses conventional vascular grafts and interventional implants for vascular and cardiac surgery and radiology and cardiology.

Edwards Lifesciences Corp. engages in patient-focused medical innovations for heart disease and critical care monitoring. Its products are categorized into four main areas: Transcatheter Aortic Valve Replacement, Transcatheter Mitral and Tricuspid Therapies, Surgical Structural Heart, and Critical Care. It operates through the following geographical segments: United States, Europe, Japan, and Rest of World. The company was founded by Miles Lowell Edwards in 1958 and is headquartered in Irvine, CA.

Cardeon Corp. develops devices based on the principle of hypothermia to protect the brain against damage during or after cardiovascular and other surgical procedures. The company's technology also segments the brain circulation from the corporeal circulation to keep the brain free of emboli. The company is located in Cupertino, CA.

Aortic Innovations LLC is an American private company located in Hillsboro Beach, FL, that operates as a biotechnology company. Ali P. Shahriari has been the CEO since 2011.

Part of LifeTech Scientific Corp., Lifetech Scientific (Shenzhen) Co. Ltd. is a Chinese company located in Shenzhen that manufactures medical devices. On July 06, 2004 ATC Technology Corp. (Arizona) acquired Lifetech Scientific (Shenzhen) Co. Ltd.

Keystone Heart aspires to be the world leader in embolic cerebral protection for cardiovascular procedures. To develop and manufacture cerebral protection devices, focused on protecting the brain from emboli to reduce the risk of brain infarcts during TAVR, AF ablation and other structural heart procedures. Cerebral function is the essence of quality of life. Preserving brain reserve throughout medical procedures is a key component to procedural success and patient care.

Medtronic Vascular designs and develops technologies for coronary, peripheral, and neurovascular indications. The company’s products include S7 Zipper MX Coronary Stent System, Clo-Sur PAD Nonwoven Hydrophilic Wound Dressing, Launcher Coronary Guide Catheter, and Stormer Over-the-Wire Balloon Dilatation Catheter. The company also offers Bridge Assurant Balloon-Expandable Stent Delivery System, GuardWire Plus Temporary Occlusion and Aspiration System, and S660 Coronary Stent. Medtronic Vascular was incorporated in 1991 and is based in Santa Rosa, California. As of January 29, 1999, Medtronic Vascular operates as a subsidiary of Medtronic.

Medtronic, Inc. operates as a medical technology company. It offers implantable cardiac pacemakers, eternal defibrillators, inferior turbinate surgery products, and continuous glucose monitoring device. The company was founded by Earl E. Bakken and Palmer J. Hermundslie on April 29, 1949 and is headquartered in Minneapolis, MN.

Shanghai Weidun Medical Technology Co., Ltd., established on 2021-05-28, Business scope includes licensed projects:Class III medical device business.(Items subject to approval by law,Business activities can only be carried out after approval by relevant departments,The specific business items are subject to the approval documents or licenses of relevant departments) General project:working in medical technology(human stem cells,Except for the development and application of genetic diagnosis and treatment technology)technology development in the field,own technology transfer,And provide relevant technical advice,Technical Services;Sales of Class I Medical Devices;Sales of Class II Medical Devices;Information Consulting Service(Not including licensing information consulting services);Import and export;Technology Import and Export.(Except for projects subject to approval by law,Carry out business activities independently in accordance with the law with a business license)

Boston Scientific Ltd., part of Boston Scientific Corp., is a British company located in Hemel Hempstead. The firm distributes medical products. It was founded in 1992.\nThe company says this about itself: Boston Scientific Ltd designed, manufactured and sold transvaginal mesh (“TVM”) medical devices that were implanted into thousands of Canadian women for the treatment of Stress Urinary Incontinence (“SUI”) and Pelvic Organ Prolapse (“POP”).

HeartWare, Inc. manufactures electro medical and electrotherapeutic apparatus. The company develops implantable circulatory assist devices, which are used in treating patients with congestive heart failure problems. The company was established in 2003 and is headquartered in Miramar, FL

Boston Scientific Scimed, Inc. develops, manufactures, and markets medical devices used principally to treat cardiovascular disease.

Contego Inc. is committed to Corporate IT Governance. Risk Management and Compliance (IT GRC), Contego is the largest "Single Source" IT GRC Services firm in Canada today. They partner with their clients to identify the most critical risks associated with their business and Information Assets. Contego then provides holistic services and solutions for effective IT risk management, mitigation and compliance management. At Contego, they make it their priority to gain a clear understanding of your organization, your business objectives and regulatory compliance requirements. they partner with you to maintain and manage your risks and compliance and support your security infrastructure. Their Services Practices allow their customers to define their “security posture” by developing policies, procedures and road maps to mitigate risks and maintain and prove compliancy throughout the year.

Materialise GmbH, a subsidiary of Materialise NV, is a company headquartered in Gilching, Germany. The firm provides additive manufacturing software and 3D printing services. It was founded in 1990 by Wilfried Vancraen. Marcus Joppe and Johan Pauwels are the current co-CEOs of the company.

Filterlex Medical Ltd. is a medical device startup in the cardiovascular field. Its goal is to develop the next generation embolic protection device for reducing the risk of stroke and other complications during catheter-based structural heart procedures. The device concept and unique structure was created out of deep understanding and knowledge of the unmet need and current products limitations and weaknesses. Filterlex is currently seeking seed funding.

Nexeon MedSystems, Inc. is a medical device company, which focuses on the development, manufacturing, and commercialization of neurostimulation technology for the treatment of various neurological disorders through electrical stimulation of neural tissues. Its neurostimulation technology platform has the potential to provide treatment to patients in several established neurostimulator markets including deep brain stimulation, peripheral electrical nerve stimulation, sacral nerve stimulation, spinal cord stimulation, vagus nerve stimulation, and other emerging neurostimulator markets. The company was founded by Mark C. Bates and Ralph L. Ballard, III in 2005 and is headquartered in Nevis Island, NV.