Symetis is a Swiss Company developing innovative minimally invasive heart valve replacement therapies for patients suffering from heart valve diseases. Symetis is dedicated to improving patient care and safety by offering simple, accurate solutions for heart valve replacement. Its proprietary Acurateâ„¢Aortic Valve Replacement System features a unique self-positioning design providing facile implant positioning and alignment as well as unrivalled ease of use.

Boston Scientific Scimed, Inc. develops, manufactures, and markets medical devices used principally to treat cardiovascular disease.

Edwards Lifesciences Corp. engages in patient-focused medical innovations for heart disease and critical care monitoring. Its products are categorized into four main areas: Transcatheter Aortic Valve Replacement, Transcatheter Mitral and Tricuspid Therapies, Surgical Structural Heart, and Critical Care. It operates through the following geographical segments: United States, Europe, Japan, and Rest of World. The company was founded by Miles Lowell Edwards in 1958 and is headquartered in Irvine, CA.

Tendyne Holdings, Inc. is a clinical stage medical device company focused on the development of minimally invasive therapies for the treatment of mitral regurgitation. Mitral regurgitation is a condition that afflicts hundreds of thousands of individuals worldwide every year. Formed in 2010, their first product concept is a transcatheter mitral valve replacement prosthesis for the treatment of mitral regurgitation. The intent is for the valve to be deployed and secured with no disruption to the native mitral annulus while preserving the sub-valvular apparatus. Placement of the valve is intended to be completed transapically in a simple procedure where the implanting physician is able to re-position, remove, and re-deploy their valve throughout the procedure.

Medtronic, Inc. operates as a medical technology company. It offers implantable cardiac pacemakers, eternal defibrillators, inferior turbinate surgery products, and continuous glucose monitoring device. The company was founded by Earl E. Bakken and Palmer J. Hermundslie on April 29, 1949 and is headquartered in Minneapolis, MN.

Venus MedTech (HangZhou) Inc. is located in Hangzhou National High-tech Industrial Development Zone (Binjiang), with its products positioned in the development and industrialization of international advanced interventional artificial cardiac valve system, filling up the blank in China. Interventional artificial aortic valve products researched and developed by the company takes the lead in finishing clinical tests in China. In reference to the development and promotion conditions of coronary stents at home and abroad, interventional artificial cardiac valve, as a revolutionary treatment means, has been increasingly recognized by experts, and will take on an explosible increase of clinical needs in the foreseeable next few years.

Boston Scientific Ltd., part of Boston Scientific Corp., is a British company located in Hemel Hempstead. The firm distributes medical products. It was founded in 1992.\nThe company says this about itself: Boston Scientific Ltd designed, manufactured and sold transvaginal mesh (“TVM”) medical devices that were implanted into thousands of Canadian women for the treatment of Stress Urinary Incontinence (“SUI”) and Pelvic Organ Prolapse (“POP”).

JenaValve Technology GmbH develops and manufactures transcatheter valve implantation systems for transapical and transfemoral implantation. The firm offers a therapeutic alternative to surgical aortic valve replacement for high-risk patients suffering from aortic heart valve stenosis. The company was founded by Markus Ferrari, Volker Guyenot and Hans-Reiner Figulla in 2006 and is headquartered in Munich, Germany.

3F Therapeutics develops, manufactures, and markets cardiovascular devices. It offers invasive and transapical aortic heart replacement technology, including enabling aortic heart valve, entrata aortic valve system, and endurance valve system to reduce surgical cross-clamp and cardio-pulmonary bypass time, utilization for congestive heart failure.

Part of Abbott Laboratories, St. Jude Medical, Cardiology Division, Inc. is a company headquartered in St. Paul, MN. The firm develops and commercializes minimally invasive cardiovascular and neurovascular medical devices. It was founded by Paul R. Buckman. Lisa D. Earnhardt is currently the CEO of the company.

Heartport is an entrepreneurial medical device maker that has introduced several innovative systems for conducting less-invasive cardiac surgery. The company was founded by John H. Stevens and Wesley D. Sterman. Heartport manufactures and markets less invasive cardiac surgery products that enable surgeons to perform a wide range of less invasive open-chest and minimally invasive heart operations, including stopped heart and beating heart procedures. In April 2001, Heartport was merged with and into CARDIOVATIONS, a wholly-owned subsidiary of Johnson & Johnson. Heartport continues to operate as a part of the division of Ethicon, Inc., a Johnson & Johnson company. Ethicon is a global leader in developing and marketing products for surgery in the areas of wound closure and wound management, surgical sports medicine, women's health and cardiovascular surgery.

Avalon Medical AS, a subsidiary of Medu AS, is a Norwegian company located in Oslo. The firm distributes medical equipment. It was founded in 1997. Sturle Andre Ramvik Gr��nbeck is the current CEO, occupying that position since 2020. Avalon Medical AS was acquired by Medu AS on May 18, 2021.

Beijing Xinmai Medical Technology Co., Ltd., established on 2021-07-08, Business scope includes technology development,technical consulting,Technology Exchange,technology transfer,Technology Promotion,Technical Services;software development;Basic software service;Computer System Services;Internet information service;Production of Class II Medical Devices;Production of Class III Medical Devices;Class III medical device business.(Market entities independently choose business projects in accordance with the law,Carry out business activities;Internet information service,Production of Class II Medical Devices,Production of Class III Medical Devices,The operation of Class III medical devices and items subject to approval according to law,Carry out business activities in accordance with the approved content after approval by relevant departments;Do not engage in the business activities of projects prohibited and restricted by the industrial policies of the state and this city.)

Medtronic 3F Therapeutics, Inc. develops, manufactures and markets cardiovascular devices. The company is headquartered in Minneapolis, MN.

Caisson Interventional is a privately held clinical-stage medical device company focused on the design, development, and clinical evaluation of a novel percutaneous mitral valve replacement system.

Lumen Biomedical, Inc. develops and commercializes interventional devices for embolic protection and thrombus removal throughout the body. It offers FiberNet embolic protection systems for the treatment of patients receiving endovascular intervention for carotid artery diseases; and Xtract, a thrombus aspiration catheter device that supports the care of segment elevation myocardial infarction. The company’s products are used in carotid artery procedures. It serves customers through distributors in the United States and Europe. The company was founded in 2003 and is based in Maple Grove, Minnesota.